Homocysteine, Serum/Plasma

1,350.00

Homocysteine is an intermediary in the sulfur-amino acid metabolism pathways, linking the methionine…

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Description

Product Constituents

INDIVIDUAL TEST

Category

CAD

Prerequisite

12 hours of fasting is recommended

Report Availability

Daily (Mon To Sat): 0500,1430,1600 Hrs Reported Same Day

Info

Homocysteine is an intermediary in the sulfur-amino acid metabolism pathways, linking the methionine cycle to the folate cycle. inborn errors of metabolism that lead to homocysteinemia or homocystinuria include cystathionine beta-synthase deficiency and various defects of methionine re-methylation. genetic defects in vitamin cofactors (vitamin b6, b12, and folate) and nutritional deficiency of b12 and folate also lead to abnormal homocysteine accumulation. as homocysteine is an indicator of acquired folate or vitamin b 12 deficiency, serum folic acid or vitamin b12 deficiency should be ruled out in case of abnormal homocysteine level. Other factors that may influence and increase plasma homocysteine include: age, smoking, poor diet/cofactor deficiencies, chronic kidney disease/renal disease & hypothyroidism. A high level of homocysteine makes a person more prone to endothelial injury, which leads to vascular inflammation, which in turn may lead to atherogenesis, which can result in ischemic injury. abnormally high levels of homocysteine in the serum, above 15 ┬Ámol/l, is a medical condition called hyperhomocysteinemia which has been claimed to be a significant risk factor for the development of a wide range of diseases, include thrombosis, neuropsychiatric illness, and fractures.